Factores Socioeconómicos Asociados a la Presencia de Malaria por Plasmodium Vivax en la Comunidad de Zungarococha, Iquitos, 2018

A study was conducted to determine the relationship between socioeconomic factors and the presence of malaria in the population of the community of Zungarococha during 2018. The present research was quantitative and the design was: non-experimental, transversal, descriptive and correlational. To obtain the sample, a simple probabilistic sampling was used and the interview technique with the survey was used as an instrument. For the analysis and interpretation of the results, the non-parametric free distribution test of Pearson Chi square categorical variables (X2) was chosen. A significant relationship was found between social factors (sex, age, marital status and degree of education) and economic (type of occupation, type of housing and average monthly income) with Plasmodium vivax malaria, but only male people are predictors, ages ranging from 18 to 24 years old, single, who live in a House made with materials other than noble and rustic materials, and whose monthly income is less than 930 soles.Se realizó un estudio para determinar la relación existente entre los factores socioeconómicos y la presencia de malaria en la población de la comunidad de Zungarococha durante el año 2018. La presente investigación fue de tipo cuantitativa y el diseño fue: no experimental, transversal, descriptivo y correlacional. Para obtener la muestra se utilizó un muestreo probabilístico simple y se utilizó la técnica de entrevista con la encuesta como instrumento. Para el análisis e interpretación de los resultados se eligió la prueba no paramétrica de libre distribución de variables categóricas Chi cuadrado de Pearson (X2). Se encontró relación significativa entre factores sociales (sexo, edad, estado civil y grado de instrucción) y económicos (tipo de ocupación, tipo de vivienda e ingreso promedio mensual) con la malaria por Plasmodium vivax, pero solo son predictores las personas de sexo masculino, cuyas edades oscilan entre 18 a 24 años, solteros, que viven en una Vivienda hecha con materiales distintos al material noble y rústicos, y cuyos ingresos mensuales son menores a 930 soles

"Candidatus Campylobacter infans" detection is not associated with diarrhea in children under the age of 2 in Peru.

A working hypothesis is that less common species of Campylobacter (other than C. jejuni and C. coli) play a role in enteric disease among children in low resource settings and explain the gap between the detection of Campylobacter using culture and culture independent methods. "Candidatus Campylobacter infans" (C. infans), was recently detected in stool samples from children and hypothesized to play a role in Campylobacter epidemiology in low- and middle-income countries (LMIC). This study determined the prevalence of C. infans in symptomatic and asymptomatic stool samples from children living in Iquitos, Peru. Stool samples from 215 children with diarrhea and 50 stool samples from children without diarrhea under the age of two were evaluated using a multiplex qPCR assay to detect Campylobacter spp. (16S rRNA), Campylobacter jejuni / Campylobacter coli (cadF gene), C. infans (lpxA), and Shigella spp. (ipaH). C. infans was detected in 7.9% (17/215) symptomatic samples and 4.0% (2/50) asymptomatic samples. The association between diarrhea and the presence of these targets was evaluated using univariate logistic regressions. C. infans was not associated with diarrhea. Fifty-one percent (75/146) of Campylobacter positive fecal samples were negative for C. jejuni, C. coli, and C. infans via qPCR. Shotgun metagenomics confirmed the presence of C. infans among 13 out of 14 positive C. infans positive stool samples. C infans explained only 20.7% of the diagnostic gap in stools from children with diarrhea and 16.7% of the gap in children without diarrhea. We posit that poor cadF primer performance better explains the observed gap than the prevalence of atypical non-C. jejuni/coli species